The Mouse CD90.2 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) 30-H12 (AGEL1218) is a cutting-edge tool for researchers focusing on CD90.2, a well-known marker for stem cells, T cells, and other cell populations. This antibody is specifically designed for flow cytometry applications, providing precise and reliable detection of CD90.2 in mouse samples.CD90.2, also known as Thy1.2, is a cell surface glycoprotein involved in cell-cell interactions, signaling, and differentiation processes. Its expression is essential for the identification and characterization of various cell types, making it a crucial target in stem cell research, immunology, and developmental biology studies.
The PE/Cyanine5.5 conjugation of this antibody offers enhanced fluorescence signal and compatibility with multicolor flow cytometry experiments.By utilizing the Mouse CD90.2 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) 30-H12 (AGEL1218), researchers can accurately analyze CD90.2-positive cell populations, investigate cellular dynamics, and advance their understanding of immune responses, tissue regeneration, and disease pathogenesis in the context of mouse models. This antibody serves as a valuable resource for scientists seeking to unravel the complexities of CD90.2 biology and its implications in diverse biological processes.
PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.