The Mouse CD90.2 Monoclonal Antibody (AF647 Conjugated, 30H12, AGEL1221) offered by AssayGenie is a cutting-edge tool for researchers studying CD90.2 expression in mouse samples. This high-quality antibody is specifically designed for applications where detection and visualization of CD90.2, a widely-used marker for murine T cells and stem cells, is crucial.With the AF647 conjugation, this antibody provides excellent signal intensity and low background noise, ensuring precise and reliable results in flow cytometry, immunofluorescence, and other techniques. The 30H12 clone used in this antibody recognizes CD90.
2 with high specificity, enabling accurate identification and characterization of CD90.2-positive cell populations.By targeting CD90.2, researchers can gain valuable insights into the role of T cells and stem cells in various physiological and pathological processes, including immune responses, tissue regeneration, and cancer development. The Mouse CD90.2 Monoclonal Antibody from AssayGenie is a versatile tool that empowers researchers to advance their understanding of mouse biology and disease mechanisms.
Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.