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FITC Anti-Mouse CD8a Antibody [53-6.7] (AGEL0380)

SKU:
AGEL0380
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
53.6.7
Conjugation:
FITC
Applications:
FC
€79 - €189
Frequently bought together:

Description

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FITC Anti-Mouse CD8a Antibody [53-6.7]

The Mouse CD8a Monoclonal Antibody (FITC Conjugated, 53-6.7) is a versatile tool for research involving CD8a, a key cell surface marker on cytotoxic T cells. This antibody, derived from hybridoma cells, offers high specificity and sensitivity for detecting CD8a expression in mouse samples, making it an essential reagent for flow cytometry analysis. It binds specifically to the CD8a protein, facilitating precise identification and characterization of CD8a+ cell populations in immune responses and disease models.CD8a is a crucial component of the immune system, playing a central role in cytotoxic T cell function and immune surveillance. Its expression level and activation status are indicators of T cell activation and differentiation, making it a valuable marker for studying immune responses in various physiological and pathological conditions.

The Mouse CD8a Monoclonal Antibody (FITC Conjugated, 53-6.7) is a reliable tool for researchers investigating T cell biology, infectious diseases, autoimmune disorders, and cancer immunotherapy.With its proven efficacy and robust performance in flow cytometry, this antibody enables precise and reliable detection of CD8a expression, allowing researchers to delve deeper into the intricate mechanisms of immune responses and T cell function. Enhance your experimental outcomes and advance your research with the Mouse CD8a Monoclonal Antibody (FITC Conjugated, 53-6.7) from AssayGenie.

Product Title:FITC Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL0380
Size:50 Tests, 100 Tests, 200 Tests
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

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