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GenieFluor 647 Anti-Mouse CD86 Antibody [GL-1] (AGEL0551)

SKU:
AGEL0551
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
GL-1
Conjugation:
AF 647
€249 - €569
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD86 Antibody [GL-1]

The Mouse CD86 Monoclonal Antibody (AF647 Conjugated) - GL-1 (AGEL0551) from Assay Genie is an essential tool for researchers studying the CD86 protein in mouse samples. CD86, also known as B7-2, is a co-stimulatory molecule that plays a crucial role in T cell activation and immune response regulation. This monoclonal antibody, conjugated with AF647 for fluorescent detection, is specifically designed to target and detect mouse CD86, enabling precise analysis of its expression levels in various cell types.With its high reactivity and specificity for mouse CD86, this antibody is a valuable asset for studies in immunology, inflammation, and autoimmunity.

By facilitating the detection and quantification of CD86, researchers can gain insights into its function and role in modulating immune responses. This information is essential for understanding the mechanisms underlying autoimmune diseases, chronic inflammation, and immune system dysregulation.Overall, the Mouse CD86 Monoclonal Antibody (AF647 Conjugated) - GL-1 (AGEL0551) offers researchers a reliable and versatile tool for investigating the role of CD86 in mouse models, opening up new avenues for research in immunology and related fields.

Product Title:GenieFluor 647 Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL0551
Size:50 Tests, 100 Tests, 200 Tests
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42082
Gene ID:12524
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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