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GenieFluor 488 Anti-Mouse CD86 Antibody [GL-1] (AGEL0550)

SKU:
AGEL0550
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$275 - $647
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD86 Antibody [GL-1]

The Mouse CD86 Monoclonal Antibody (AF488 Conjugated) - GL-1 (AGEL0550) offered by AssayGenie is a cutting-edge tool for immunological research. This monoclonal antibody specifically targets CD86, a vital co-stimulatory molecule involved in T cell activation and immune response regulation. By coupling the AF488 fluorophore to the antibody, AssayGenie ensures high sensitivity and precision in fluorescence-based assays.CD86, also known as B7-2, is a key immune checkpoint molecule that plays a crucial role in modulating immune activation and tolerance. Its interaction with CD28 on T cells is essential for effective T cell proliferation and cytokine production. The Mouse CD86 Monoclonal Antibody (AF488 Conjugated) - GL-1 (AGEL0550) enables researchers to study CD86 expression and localization in various biological samples, providing valuable insights into immune responses, autoimmune diseases, and vaccine development.

This innovative antibody is ideal for flow cytometry, immunofluorescence, and immunohistochemistry applications, allowing for detailed analysis of CD86 expression patterns in different cell populations. With its high specificity and efficiency, the Mouse CD86 Monoclonal Antibody (AF488 Conjugated) - GL-1 (AGEL0550) from AssayGenie is a powerful tool for advancing immunology research and understanding the complex mechanisms of immune regulation.

Product Title:GenieFluor 488 Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL0550
Size:50 Tests, 100 Tests, 200 Tests
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42082
Gene ID:12524
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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