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PE/Cyanine5 Anti-Mouse CD80 Antibody [16-10A1] (AGEL0535)

SKU:
AGEL0535
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
16-10A1
Conjugation:
PE/Cy5
$215 - $551
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD80 Antibody [16-10A1]

The Mouse CD80 Monoclonal Antibody PE/Cyanine5 Conjugated (16-10A1) is a valuable tool for research in immunology and cell biology. This antibody is specifically designed to target CD80, a co-stimulatory molecule involved in T cell activation and regulation of the immune response. By utilizing this antibody, researchers can accurately detect and analyze CD80 expression in mouse samples, providing insights into immune cell interactions and functions. The PE/Cyanine5 conjugation allows for multiparameter flow cytometry analysis, enabling detailed characterization of immune cell populations in experimental settings.

CD80, also known as B7-1, plays a crucial role in modulating T cell activation and tolerance, making it a key player in immune responses and autoimmune diseases. The ability to specifically target CD80 with this monoclonal antibody opens up possibilities for studying its functions in various cellular contexts and disease models.Overall, the Mouse CD80 Monoclonal Antibody PE/Cyanine5 Conjugated (16-10A1) is a valuable resource for researchers seeking to deepen their understanding of immune regulation and T cell activation processes in mouse models.

Product Title:PE/Cyanine5 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL0535
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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