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PE Anti-Mouse CD80 Antibody [16-10A1] (AGEL0533)

SKU:
AGEL0533
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€119 - €289
Frequently bought together:

Description

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PE Anti-Mouse CD80 Antibody [16-10A1]

The Mouse CD80 Monoclonal Antibody (PE Conjugated, 16-10A1, AGEL0533) offered by AssayGenie is a cutting-edge tool designed for researchers working with mouse models. This high-quality antibody is specifically engineered to target CD80, a crucial cell surface molecule involved in immune regulation and T cell co-stimulation.Derived from mouse hybridoma 16-10A1, this monoclonal antibody is conjugated to phycoerythrin (PE), enabling precise and sensitive detection of CD80. With its exceptional specificity and reactivity, this antibody is ideal for flow cytometry applications, allowing for accurate identification and analysis of CD80 expression on various cell types in mouse samples.

CD80, also known as B7-1, plays a vital role in the activation and regulation of T cells, making it a key focus in immunology research. By utilizing the Mouse CD80 Monoclonal Antibody (PE Conjugated, 16-10A1, AGEL0533), researchers can gain valuable insights into the function of CD80 in immune responses, autoimmune diseases, and other related conditions in mouse models.With its reliability, versatility, and consistent performance, this antibody from AssayGenie is an essential tool for scientists conducting studies in immunology, cancer research, and beyond. Unlock the potential of CD80 research in mouse models with the help of this innovative monoclonal antibody.

Product Title:PE Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL0533
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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