The Mouse CD73 Monoclonal Antibody PE Conjugated (TY/23) is a powerful tool for researchers studying CD73, an important cell surface protein with roles in immune regulation and inflammation. This monoclonal antibody, conjugated with the fluorophore PE, is specifically designed for flow cytometry applications, allowing for precise detection and analysis of CD73-expressing cells in various experimental settings.CD73, also known as ecto-5'-nucleotidase, is a key enzyme involved in the production of adenosine, a molecule with potent immunomodulatory effects. By catalyzing the conversion of AMP to adenosine, CD73 plays a critical role in regulating immune responses, inflammatory processes, and tissue homeostasis. Research into CD73 function is essential for understanding its impact on the immune system and its potential as a therapeutic target in conditions such as cancer, inflammatory diseases, and tissue injury.
With its high specificity and sensitivity, the Mouse CD73 Monoclonal Antibody PE Conjugated (TY/23) is a valuable tool for investigating the expression and function of CD73 in various biological systems. Its application in flow cytometry enables researchers to analyze cell populations, characterize immune cell subsets, and evaluate the role of CD73 in immune regulation and disease pathogenesis. This antibody is a versatile resource for studies in immunology, oncology, and inflammation, providing insights that may contribute to the development of novel therapies targeting CD73-mediated pathways.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q61503
Gene ID:
23959
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD73 (ecto-5`-nucleotidase) is a 69 kD GPI-anchored surface protein. In mice, expression of CD73 in bone marrow is restricted to CD11b+ myeloid cells. In spleen, it is largely expressed on T cells.