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APC Anti-Mouse CD73 Antibody [TY/23] (AGEL1144)

SKU:
AGEL1144
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€159 - €389
Frequently bought together:

Description

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APC Anti-Mouse CD73 Antibody [TY/23]

The Mouse CD73 Monoclonal Antibody (APC Conjugated, TY-23) is a specialized tool for research involving CD73, a key enzyme involved in purine metabolism and immune regulation. This monoclonal antibody, specifically designed for mouse samples, is conjugated with allophycocyanin (APC) for easy detection and analysis in flow cytometry and immunofluorescence applications. CD73, also known as ecto-5'-nucleotidase, plays a crucial role in generating adenosine, a potent immunosuppressive molecule with implications in inflammation, cancer, and tissue repair. By targeting CD73, researchers can explore its role in modulating the immune response and its potential as a therapeutic target in various diseases.

This antibody, clone TY-23, offers high specificity and sensitivity in recognizing the CD73 protein on cell surfaces, allowing for precise detection and quantification in different cell populations. Its application in immunology, oncology, and drug development makes it a valuable tool for unraveling the complex interplay between purinergic signaling and immune regulation. By studying CD73 with this monoclonal antibody, researchers can gain insights into novel therapeutic strategies and mechanisms underlying immune-related disorders.

Product Title:APC Anti-Mouse CD73 Antibody [TY/23]
SKU:AGEL1144
Size:25µg, 100µg
Clone No:TY/23
Synonyms:5'-nucleotidase;Nt5e;5'-NT;Ecto-5'-nucleotidase;CD73;Nt5; Nte;Nt5e;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q61503
Gene ID:23959
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD73 (ecto-5`-nucleotidase) is a 69 kD GPI-anchored surface protein. In mice, expression of CD73 in bone marrow is restricted to CD11b+ myeloid cells. In spleen, it is largely expressed on T cells.

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