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PE/Cyanine7 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL1200)

SKU:
AGEL1200
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€219 - €519
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody PE/Cyanine7 Conjugated (R17-217.1-3/TIB-219) is a powerful tool for researchers investigating CD71, a cell surface marker involved in transferrin uptake and iron metabolism. This antibody, derived from mouse hybridoma cells, exhibits strong reactivity with mouse samples and is optimized for flow cytometry applications. By specifically binding to the CD71 antigen, it enables precise detection and analysis of CD71 expression in various cell populations, making it an essential tool for studies in immunology, cell biology, and cancer research.

CD71, also known as transferrin receptor protein 1, plays a crucial role in cellular iron uptake and is commonly upregulated in rapidly dividing cells such as cancer cells. Understanding the expression and regulation of CD71 is key to unraveling its role in iron homeostasis, cell proliferation, and disease progression. This antibody provides researchers with a reliable means to study CD71 dynamics in different cell types, aiding in the investigation of iron metabolism, cancer biology, and potential therapeutic interventions targeting CD71-expressing cells.

Product Title:PE/Cyanine7 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL1200
Size:25µg, 100µg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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