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PE Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL1197)

SKU:
AGEL1197
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
R17 217.1.3/TIB-219
Conjugation:
PE
€129 - €309
Frequently bought together:

Description

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PE Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody (PE-conjugated, R17 217.1.3/TIB-219, AGEL1197) is a vital tool for researchers studying CD71, a critical cell surface marker associated with iron uptake and cellular proliferation. This monoclonal antibody, specifically designed for use in flow cytometry, immunofluorescence, and immunohistochemistry applications, offers high specificity and sensitivity in detecting CD71 in mouse samples.CD71, also known as transferrin receptor protein 1, plays a crucial role in iron metabolism by facilitating the uptake of transferrin-bound iron into cells. Its overexpression is often associated with increased cellular proliferation, making it a key marker in cancer research and studies of cell cycle regulation.

By targeting CD71 with this antibody, researchers can gain valuable insights into iron metabolism, proliferation pathways, and potential therapeutic targets in diseases such as cancer and anemia.This PE-conjugated monoclonal antibody provides a convenient and reliable tool for visualizing and analyzing CD71 expression in various cell types and tissues. With its high specificity and performance in multiple experimental techniques, this antibody is an essential component for investigations into iron homeostasis, cell proliferation, and therapeutic interventions targeting CD71-mediated pathways.

Product Title:PE Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL1197
Size:25µg, 100µg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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