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Biotin Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL0339)

SKU:
AGEL0339
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
R17 217.1.3/TIB-219
Conjugation:
Biotin
Applications:
FC
€99 - €179
Frequently bought together:

Description

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Biotin Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody (Biotin Conjugated) R17-217.1.3 (TIB-219) (AGEL0339) is a specialized antibody developed for research applications involving CD71, a cell surface marker associated with iron metabolism and cell proliferation. This biotin-conjugated antibody, derived from a mouse source, exhibits high specificity and sensitivity for detecting CD71 in mouse samples, particularly in flow cytometry and immunohistochemistry experiments.CD71, also known as Transferrin Receptor Protein 1, plays a crucial role in cellular iron uptake, making it essential for processes like erythropoiesis and cell growth. Its expression levels are often elevated in rapidly dividing cells, making it a valuable marker for studying cell cycle progression, proliferation, and iron metabolism.

Researchers in fields such as hematopoiesis, oncology, and developmental biology can benefit from utilizing this antibody to explore the functions and regulation of CD71 in various biological contexts.The ability of the Mouse CD71 Monoclonal Antibody (Biotin Conjugated) to specifically target and detect CD71 in mouse samples provides researchers with a powerful tool for delving into the roles and mechanisms of this important cell surface protein. By enabling precise and reliable detection of CD71, this antibody facilitates detailed analysis and characterization of cell populations expressing this marker, opening up avenues for deeper insights into processes related to iron homeostasis, cell proliferation, and disease pathogenesis.

Product Title:Biotin Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL0339
Size:25µg, 100µg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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