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PE/Cyanine5.5 Anti-Mouse CD62L Antibody [Mel14] (AGEL0631)

SKU:
AGEL0631
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€139 - €299
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD62L Antibody [Mel14]

The Monoclonal Antibody PE-Cyanine5.5 Conjugated Mel-14 (AGEL0631) offered by Assay Genie is a vital tool for researchers studying the mouse CD62L molecule. CD62L, also known as L-selectin, is a cell surface adhesion molecule that plays a crucial role in the immune response by facilitating lymphocyte rolling and homing to secondary lymphoid organs. This monoclonal antibody is specifically designed to target mouse CD62L and is conjugated with PE-Cyanine5.5, enabling easy detection and analysis in flow cytometry and other immunological assays. By binding to CD62L, researchers can investigate its expression levels and localization in different cell populations, providing valuable insights into immune cell trafficking and activation.

This product is ideal for studies focusing on immune cell migration, lymphocyte activation, and inflammatory responses. Understanding the function of CD62L in the immune system can lead to advancements in the treatment of various immune-related diseases, such as autoimmune disorders and inflammatory conditions. With its high specificity and reactivity, the Monoclonal Antibody PE-Cyanine5.5 Conjugated Mel-14 (AGEL0631) is a valuable tool for immunologists and researchers exploring the intricacies of mouse CD62L biology.

Product Title:PE/Cyanine5.5 Anti-Mouse CD62L Antibody [Mel14]
SKU:AGEL0631
Size:50 Tests, 100 Tests, 200 Tests
Clone No:Mel14
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P18337
Gene ID:20343
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

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