null

GenieFluor 647 Anti-Mouse CD62L Antibody [Mel14] (AGEL0643)

SKU:
AGEL0643
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€199 - €459
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 647 Anti-Mouse CD62L Antibody [Mel14]

The Mouse CD62L Monoclonal Antibody (AF647 Conjugated, Mel14, AGEL0643) offered by Assay Genie is a valuable tool for researchers studying immune cell migration and activation. This antibody specifically targets CD62L, a cell adhesion molecule involved in the homing of lymphocytes to secondary lymphoid tissues. With the AF647 conjugation, this antibody allows for fluorescent detection, making it suitable for flow cytometry and immunofluorescence applications.CD62L, also known as L-selectin, is a key molecule in the immune system, facilitating the movement of lymphocytes to sites of inflammation and infection.

By targeting CD62L, researchers can gain insights into the mechanisms underlying immune cell trafficking and the regulation of immune responses. This monoclonal antibody provides a reliable tool for investigating the role of CD62L in various physiological and pathological conditions, including inflammatory diseases, infection, and cancer.For researchers focused on understanding immune cell behavior and the modulation of immune responses, the Mouse CD62L Monoclonal Antibody (AF647 Conjugated, Mel14, AGEL0643) from Assay Genie is an essential reagent for their studies.

Product Title:GenieFluor 647 Anti-Mouse CD62L Antibody [Mel14]
SKU:AGEL0643
Size:25µg, 100µg
Clone No:Mel14
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P18337
Gene ID:20343
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Related Products