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PE/Cyanine5.5 Anti-Mouse CD54 Antibody [YN1/1.7.4] (AGEL0716)

SKU:
AGEL0716
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€239 - €539
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD54 Antibody [YN1/1.7.4]

The Mouse CD54 Monoclonal Antibody (PE-Cyanine5.5 Conjugated, YN1/1.7.4) is a valuable tool for researchers studying CD54, a cell adhesion molecule involved in immune response and inflammation regulation. This antibody, conjugated with PE-Cyanine5.5, allows for convenient flow cytometry analysis and fluorescence microscopy applications.CD54, also known as intercellular adhesion molecule 1 (ICAM-1), is critical for immune cell recruitment and interaction during inflammatory responses. By targeting CD54, researchers can investigate the role of this molecule in various diseases such as infections, autoimmune disorders, and inflammatory conditions.

The specificity and high reactivity of the Mouse CD54 Monoclonal Antibody make it a reliable choice for studies aiming to understand the mechanisms behind immune cell adhesion and migration.With its ability to bind to CD54 and facilitate its visualization in different cell types, this antibody is a valuable resource for immunologists, cell biologists, and researchers working on elucidating the complex interplay of immune molecules in health and disease. realizado.

Product Title:PE/Cyanine5.5 Anti-Mouse CD54 Antibody [YN1/1.7.4]
SKU:AGEL0716
Size:25µg, 100µg
Clone No:YN1/1.7.4
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P13597
Gene ID:15894
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

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