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GenieFluor 488 Anti-Mouse CD49b Antibody [DX5] (AGEL0442)

SKU:
AGEL0442
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgM
Clone:
DX5
Conjugation:
AF 488
Applications:
FC
€159 - €389
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD49b Antibody [DX5]

The Mouse CD49b Monoclonal Antibody (Alexa Fluor 488 Conjugated, DX5) is a cutting-edge tool for researchers delving into immunology and cell biology. Specifically targeting CD49b, a crucial cell adhesion receptor involved in immune cell trafficking and tissue homing, this antibody offers precise and reliable detection capabilities in various experimental settings.CD49b, also known as integrin alpha-2, plays a significant role in mediating cell interactions with extracellular matrix components, thereby influencing processes like immune cell migration and tissue repair. By targeting CD49b with this monoclonal antibody, researchers can elucidate its mechanisms of action in different cell types and explore its implications in various physiological and pathological conditions.

Utilizing the advanced technology of Alexa Fluor 488 conjugation, this monoclonal antibody provides exceptional sensitivity and fluorescence properties, enabling clear visualization and accurate quantification of CD49b expression. Whether investigating immune cell behavior, studying tissue-specific responses, or exploring therapeutic targets, the Mouse CD49b Monoclonal Antibody (Alexa Fluor 488 Conjugated, DX5) presents a valuable tool for advancing scientific knowledge and discovering novel insights in the field of immunology.

Product Title:GenieFluor 488 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL0442
Size:50 Tests, 100 Tests, 200 Tests
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:Genie Fluor 488 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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