The Mouse CD48 Monoclonal Antibody (PE/Cyanine7 Conjugated, HM48-1) from Assay Genie (AGEL0698) is a cutting-edge tool designed for researchers investigating CD48, a cell surface protein involved in immune responses and cell signaling pathways. This monoclonal antibody, specifically engineered for use in flow cytometry applications, offers high specificity and sensitivity in detecting CD48 expression in mouse samples.CD48, also known as BCM1 (B-lymphocyte activation marker), is a crucial molecule involved in regulating immune responses, cell adhesion, and activation of immune cells. Understanding its role in immune regulation can provide valuable insights into various diseases, including autoimmune disorders, infectious diseases, and cancer.
By targeting CD48 with this highly specific monoclonal antibody, researchers can explore its functions in different cell types and tissues, paving the way for innovative discoveries in immunology and therapeutic development.The PE/Cyanine7 conjugation of this antibody allows for multi-color flow cytometry experiments, enabling simultaneous detection of CD48 alongside other markers, enhancing the depth of analysis and accuracy of results. With its validated performance and reliability, the Mouse CD48 Monoclonal Antibody (PE/Cyanine7 Conjugated, HM48-1) represents a powerful tool for unraveling the complexities of CD48 biology and its implications in various pathological conditions.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P18181
Gene ID:
12506
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.