The Mouse CD48 Monoclonal Antibody (Biotin Conjugated) (HM48-1) is a valuable tool for researchers studying CD48, a cell surface protein involved in immune regulation and cell communication. This monoclonal antibody, designed for use in mouse samples, offers high specificity and sensitivity for detecting CD48 in various experimental applications.CD48, a signaling molecule found on immune cells, plays a crucial role in immune responses, including T cell activation and antigen presentation. By targeting CD48 with this monoclonal antibody, researchers can gain insights into the function and expression patterns of this protein in different cell types and biological processes.The biotin conjugation of this monoclonal antibody allows for easy detection and analysis using standard laboratory techniques such as flow cytometry, immunohistochemistry, and Western blotting.
With its ability to specifically bind to CD48, researchers can explore the involvement of this protein in immune system dynamics, inflammatory responses, and potential therapeutic targets in diseases such as autoimmune disorders and cancer.Overall, the Mouse CD48 Monoclonal Antibody (Biotin Conjugated) (HM48-1) is a versatile research tool that offers precise detection and characterization of CD48 in mouse samples, making it an essential component for studies in immunology, oncology, and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P18181
Gene ID:
12506
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.