null

PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1404)

SKU:
AGEL1404
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€149 - €379
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody PE-Cyanine7 Conjugated (RA3-6B2) is a valuable tool for researchers studying immune cells in mice. This antibody, conjugated with PE-Cyanine7, specifically targets the CD45R/B220 protein, a marker predominantly expressed on B cells and a subset of T cells in mice.CD45R/B220, also known as B220 antigen, is involved in B cell development and activation, making it a key player in the immune response. By targeting this protein, researchers can effectively identify and analyze B cells in various experimental settings, aiding in the investigation of immune function, autoimmune diseases, and lymphoproliferative disorders in mouse models.

The conjugation with PE-Cyanine7 allows for bright and stable fluorescence, enabling precise detection and visualization of CD45R/B220-expressing cells in flow cytometry and immunofluorescence applications. With its high specificity and sensitivity, this monoclonal antibody is a reliable tool for researchers seeking to further understand the role of B cells in immune responses and diseases in mouse models.For more detailed information and to order the Mouse CD45R/B220 Monoclonal Antibody PE-Cyanine7 Conjugated (RA3-6B2), please visit the provided URL.

Product Title:PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1404
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

Related Products