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PE Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL0423)

SKU:
AGEL0423
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgM
Clone:
RA3.3A 1/6.1
Conjugation:
PE
Applications:
FC
$131 - $335
Frequently bought together:

Description

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PE Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R / B220 Monoclonal Antibody (PE Conjugated, RA3-6B2) is a valuable tool for research involving the CD45R / B220 marker, which is commonly used to identify B cells and subsets of T cells in mice. This antibody, conjugated to the fluorescent protein PE, specifically targets the CD45R / B220 antigen, allowing for precise detection and analysis in various experimental settings.The RA3-6B2 antibody is highly specific and reliable, making it suitable for flow cytometry applications and immunophenotyping studies. By targeting the CD45R / B220 marker, researchers can accurately distinguish different immune cell populations in mouse samples, aiding in the investigation of immune responses, autoimmune diseases, and lymphoproliferative disorders.

Understanding the expression and function of CD45R / B220 is essential for advancing our knowledge of immune cell biology and developing targeted therapies for immunological disorders. The RA3-6B2 antibody provides researchers with a powerful tool to explore the role of CD45R / B220 in immune regulation and disease pathogenesis, making it an indispensable asset for immunology and immunotherapy research.

Product Title:PE Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL0423
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:PE Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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