The Mouse CD45 Monoclonal Antibody (PERCP Conjugated, 30-F11) offered by AssayGenie (Product code: AGEL1660) is a vital tool for researchers working in immunology and cell biology. This antibody is specifically designed for the detection of CD45, a well-known marker for leukocytes, on mouse cell surfaces.CD45, also known as the leukocyte common antigen, is a key regulator of immune cell activation and function. The PERCP conjugation of this monoclonal antibody allows for easy identification of CD45-expressing cells using flow cytometry, facilitating the precise analysis of immune cell populations in various experimental settings.
With its high specificity and sensitivity, the Mouse CD45 Monoclonal Antibody (PERCP Conjugated, 30-F11) from AssayGenie provides researchers with a reliable tool for studying immune cell subsets in both physiological and pathological conditions. Whether investigating immune responses in infection, inflammation, or cancer, this antibody enables accurate and detailed profiling of CD45 expression, contributing to a better understanding of immune system dynamics.Choose AssayGenie's Mouse CD45 Monoclonal Antibody (PERCP Conjugated, 30-F11) for your research needs and unlock new insights into the complexities of immune cell biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06800
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.