GenieFluor 488 Anti-Mouse CD45 Antibody [30-F11] (AGEL1675)
- SKU:
- AGEL1675
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FC
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgG2a,k
- Clone:
- 30-F11
- Conjugation:
- AF 488
Frequently bought together:
Description
Product Title: | GenieFluor 488 Anti-Mouse CD45 Antibody [30-F11] |
SKU: | AGEL1675 |
Size: | 25µg, 100µg |
Clone No: | 30-F11 |
Synonyms: | Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45; |
Host Species: | Rat |
Reactivity: | Mouse |
Application: | FCM |
Isotype: | Rat IgG2b, κ |
Isotype Control: | Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2] |
Form: | Liquid |
Conjugation: | Genie Fluor488 |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
Spectrum: |
Swissprot: | P06800 |
Gene ID: | 19264 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1. |