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FITC Anti-Mouse CD45.1 Antibody [A20] (AGEL1948)

SKU:
AGEL1948
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€99 - €189
Frequently bought together:

Description

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FITC Anti-Mouse CD45.1 Antibody [A20]

The Mouse CD45.1 Monoclonal Antibody (FITC Conjugated, clone A20) is a valuable tool for researchers studying the CD45.1 antigen in mouse samples. This antibody specifically targets the CD45.1 protein, which is a member of the protein tyrosine phosphatase family known for its role in immune cell regulation and activation.With its FITC conjugation, this antibody offers the advantage of fluorescent detection, allowing for precise visualization and analysis of CD45.1-expressing cells in flow cytometry and immunofluorescence applications. The high specificity and sensitivity of this monoclonal antibody ensure reliable results for identifying and characterizing CD45.

1-positive immune cell populations in diverse experimental settings.The CD45.1 antigen, a variant of CD45 expressed on certain mouse strains, is crucial for understanding immune cell development, activation, and function. By using the Mouse CD45.1 Monoclonal Antibody (FITC Conjugated, clone A20), researchers can investigate the roles of CD45.1-expressing cells in immune responses, autoimmune disorders, inflammation, and other physiological processes. This antibody is a valuable asset for immunologists and researchers delving into the intricacies of mouse immune system dynamics.

Product Title:FITC Anti-Mouse CD45.1 Antibody [A20]
SKU:AGEL1948
Size:25µg, 100µg
Clone No:A20
Synonyms:Ly-5;L-CA;T200;CD45;Ptprc;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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