The Mouse CD41 Monoclonal Antibody FITC Conjugated (MWReg30) (AG-EL1942) offered by AssayGenie is a specialized tool for researchers studying CD41, an important cell surface marker associated with platelets and megakaryocytes. This monoclonal antibody, derived from mice and conjugated with FITC for fluorescent detection, exhibits high specificity and sensitivity in detecting CD41 protein in mouse samples.CD41, also known as integrin alpha 2b, is a key player in platelet aggregation and blood clotting processes. Its expression is essential for proper platelet function and thrombosis regulation. Research involving CD41 is crucial for understanding various hematological disorders, cardiovascular diseases, and thrombotic conditions.
This FITC-conjugated monoclonal antibody allows for precise visualization and analysis of CD41 expression in different cell types and tissues, making it suitable for flow cytometry, immunofluorescence, and other experimental techniques. By targeting CD41, researchers can delve deeper into the mechanisms of thrombosis, platelet activation, and other biological processes related to this important cell surface marker.Enhance your studies in hematology, cardiovascular research, and thrombosis investigations with the Mouse CD41 Monoclonal Antibody FITC Conjugated (MWReg30) (AG-EL1942) from AssayGenie.
Product Title:
FITC Anti-Mouse CD41 Antibody [MWReg30]
SKU:
AGEL1942
Size:
25µg, 100µg
Clone No:
MWReg30
Synonyms:
Itga2b;GPalpha Iib;CD41;GPIIb;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
FITC Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q9QUM0
Gene ID:
16399
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.