null

PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0788)

SKU:
AGEL0788
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
FGK4.5/FGK45
Conjugation:
PerCP/Cy5.5
€219 - €539
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, FGK4.5) is a specialized tool for researchers studying CD40, a critical cell surface receptor involved in immune responses and inflammation regulation. This antibody, conjugated with PerCP-Cyanine5.5, offers high sensitivity and specificity in detecting CD40 expression in various biological samples. CD40 is a key protein found on the surface of immune cells and is known for its role in immune activation, particularly in the context of antigen presentation and T cell activation. By targeting CD40, researchers can gain insights into immune system function, autoimmune diseases, and potential therapeutic interventions targeting this pathway.

The FGK4.5 Monoclonal Antibody is highly specific to mouse CD40, making it an invaluable tool for cell biology, immunology, and cancer research. With its exceptional reactivity and validated performance, this antibody facilitates precise detection and analysis of CD40 expression, contributing to a deeper understanding of immune responses and the development of novel treatment strategies.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0788
Size:25µg, 100µg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Related Products