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PE/Cyanine7 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0786)

SKU:
AGEL0786
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€219 - €539
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (PE/Cyanine7 Conjugated, FGK4.5) is a vital tool for researchers studying the CD40 protein in mouse samples. This antibody, derived from FGK4.5 hybridoma cells, is conjugated with PE/Cyanine7 for fluorescent detection, facilitating precise and reliable analysis in flow cytometry and immunofluorescence assays. CD40 is a cell surface receptor with diverse functions in immune responses, including B cell activation and antigen presentation, making it a key target in immunology and cancer research.

The binding specificity of this antibody to the CD40 protein allows for accurate identification and quantification of CD40 expression in various cell populations, aiding in the investigation of immune cell interactions and signaling pathways. By utilizing this antibody, researchers can gain insights into the role of CD40 in autoimmune diseases, inflammatory conditions, and cancer progression, leading to potential therapeutic interventions targeting the CD40 pathway.

Product Title:PE/Cyanine7 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0786
Size:25µg, 100µg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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