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PE Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0783)

SKU:
AGEL0783
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
FGK4.5/FGK45
Conjugation:
PE
€169 - €459
Frequently bought together:

Description

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PE Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (PE conjugated) - FGK4.5 (FGK45) (AGEL0783) is a vital tool for researchers studying immune responses and cell signaling pathways. This monoclonal antibody, designed for use in flow cytometry applications, specifically targets the CD40 protein on mouse cells. By conjugating the antibody with PE (phycoerythrin), it allows for easy and efficient detection of CD40 expression levels in various cell populations.CD40 is a key cell surface receptor involved in immune regulation and activation. Its interaction with CD40 ligand plays a crucial role in the activation and differentiation of immune cells, making it a key player in adaptive immunity.

The FGK4.5 (FGK45) antibody offers high specificity and sensitivity in detecting CD40, making it an ideal tool for studies focusing on immune responses, inflammation, and immune cell activation pathways in mouse models.Researchers interested in studying immune responses, B cell activation, and antibody production in mouse models will find the Mouse CD40 Monoclonal Antibody (PE conjugated) - FGK4.5 (FGK45) (AGEL0783) to be a valuable asset. With its reliable performance and specific targeting of CD40, this antibody opens up new possibilities for understanding immune signaling pathways and developing targeted immunotherapies for various diseases.

Product Title:PE Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0783
Size:25µg, 100µg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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