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FITC Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0782)

SKU:
AGEL0782
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€119 - €269
Frequently bought together:

Description

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FITC Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (FITC Conjugated, FGK4.5/FGK45) from Assay Genie (AGEL0782) is a powerful tool designed for researchers studying the CD40 protein in mice. The antibody, developed using cutting-edge technology, is conjugated with FITC for fluorescent detection, providing precise and reliable results in various immunoassays and flow cytometry applications.CD40 is a crucial cell surface receptor involved in immune responses, particularly in the activation of B cells and antigen-presenting cells. By targeting CD40 with this monoclonal antibody, researchers can investigate the function and expression of this protein in different cell types and experimental settings, shedding light on immune system regulation and potential therapeutic targets.

Validated for specificity and sensitivity, this antibody enables accurate detection and analysis of CD40 in mouse samples, making it an indispensable tool for research in immunology, inflammation, and autoimmune disorders. Explore the intricate roles of CD40 in immune signaling pathways and discover new insights into immune cell interactions with the Mouse CD40 Monoclonal Antibody from Assay Genie.

Product Title:FITC Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0782
Size:25µg, 100µg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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