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FITC Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0775)

SKU:
AGEL0775
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€169 - €389
Frequently bought together:

Description

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FITC Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (FITC Conjugated, FGK4.5/FGK45) is a cutting-edge tool designed for researchers exploring the role of CD40, a vital cell surface molecule involved in immune responses and signaling. This monoclonal antibody, conjugated with FITC for fluorescent detection, is specifically engineered for use in various experimental applications, including flow cytometry and immunofluorescence microscopy.CD40 is a key player in the immune system, serving as a co-stimulatory molecule essential for the activation of B cells and antigen-presenting cells. Its interactions are crucial for adaptive immune responses, making it a significant target for studies focused on immunology, vaccine development, and autoimmune diseases. The precise binding of this monoclonal antibody to CD40 facilitates its detection and analysis in diverse cell types, providing researchers with an invaluable tool for investigating immune regulation mechanisms and developing novel therapeutic strategies.

Combining the specificity of FGK4.5/FGK45 monoclonal antibody with the versatility of FITC conjugation offers researchers a powerful means to visualize and study the dynamics of CD40 expression and function in biological systems. Whether investigating immune cell activation pathways, exploring immune checkpoint mechanisms, or assessing immune cell interactions, the Mouse CD40 Monoclonal Antibody is a trusted companion in unraveling the complexities of immune responses and advancing biomedical research.

Product Title:FITC Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0775
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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