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PE/Cyanine5.5 Anti-Mouse CD4 Antibody [GK1.5] (AGEL1251)

SKU:
AGEL1251
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€199 - €459
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD4 Antibody [GK1.5]

The Mouse CD4 Monoclonal Antibody PE-Cyanine5.5 Conjugated (GK1.5) is a valuable tool for research in immunology and cell biology. This antibody specifically targets the CD4 molecule, a key cell surface marker involved in immune responses and T cell activation. By conjugating PE-Cyanine5.5 to the antibody, it enables fluorescent detection and analysis of CD4 expression in various cell types.CD4, a glycoprotein found on the surface of helper T cells, plays a pivotal role in coordinating immune responses by interacting with major histocompatibility complex (MHC) class II molecules. The GK1.5 antibody, derived from mouse hybridoma cells, recognizes CD4 with high specificity and sensitivity, allowing for precise identification and characterization of CD4-expressing cells.

Researchers can utilize this antibody for flow cytometry, immunofluorescence, and other techniques to study T cell subsets, immune function, and diseases such as HIV/AIDS, autoimmune disorders, and infectious diseases. The PE-Cyanine5.5 conjugation enhances the detection sensitivity and multiplexing capabilities, making it a versatile tool for studying immune cell populations and responses in both basic and clinical research settings.

Product Title:PE/Cyanine5.5 Anti-Mouse CD4 Antibody [GK1.5]
SKU:AGEL1251
Size:25µg, 100µg
Clone No:GK1.5
Synonyms:T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;L3T4;T4;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P06332
Gene ID:12504
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.

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