The Mouse CD4 Monoclonal Antibody (PE Conjugated) GK1.5 (AGEL0356) is an essential tool for researchers studying immune responses and T cell biology. This antibody specifically targets the CD4 protein, a key cell surface marker found on helper T cells involved in coordinating immune responses. The GK1.5 antibody is conjugated with phycoerythrin (PE), enabling easy and efficient fluorescent detection of CD4-expressing cells using flow cytometry or fluorescence microscopy techniques. Its high specificity and sensitivity make it a valuable tool for identifying, quantifying, and analyzing CD4-positive cells in various biological samples.With its ability to precisely target CD4 molecules, the GK1.
5 antibody is a crucial asset in immunology research, particularly in investigating T cell function, immune system development, and immune-related diseases. Whether studying immune cell populations in basic research or evaluating potential therapeutic interventions, this antibody provides reliable and accurate results for a wide range of experimental applications. Overall, the Mouse CD4 Monoclonal Antibody (PE Conjugated) GK1.5 (AGEL0356) is a versatile reagent that empowers scientists to delve deeper into the complexities of immune responses and T cell biology, driving advancements in our understanding of immune system dynamics and contributing to the development of novel immunotherapies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.