The Mouse CD4 Monoclonal Antibody (Biotin Conjugated) GK1.5 (AGEL0354) featured on www.assaygenie.com is a powerful tool for immunological research. This antibody, derived from the GK1.5 hybridoma, is specifically engineered to target the CD4 molecule, a key marker of T cells.Designed for use in various immunoassays, flow cytometry, and immunohistochemistry, the Mouse CD4 Monoclonal Antibody (Biotin Conjugated) GK1.5 (AGEL0354) offers high specificity and sensitivity. It enables precise detection and analysis of CD4 expression in mouse samples, making it an invaluable resource for researchers studying T cell biology, immune responses, and autoimmune disorders.
With its biotin conjugation, this antibody facilitates easy and efficient labeling for a range of experimental techniques, allowing for detailed investigation of CD4-positive cell populations. By targeting CD4, a pivotal protein involved in immune function and cell signaling, this antibody contributes to a deeper understanding of T cell biology and immune system dynamics.In summary, the Mouse CD4 Monoclonal Antibody (Biotin Conjugated) GK1.5 (AGEL0354) is a versatile and reliable tool for immunological research, offering researchers a precise means to study CD4-expressing cells in mouse models with exceptional accuracy and specificity.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.