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GenieFluor 488 Anti-Mouse CD4 Antibody [GK1.5] (AGEL1253)

SKU:
AGEL1253
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
GK1.5
Conjugation:
AF 488
€209 - €429
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD4 Antibody [GK1.5]

The Mouse CD4 Monoclonal Antibody (AF488 Conjugated, GK1.5) AGEL1253 is a specialized tool for immunological research, particularly in the analysis of CD4, a crucial cell surface marker involved in immune responses. This antibody, conjugated with AF488 for fluorescent detection, is specifically designed for use in flow cytometry and immunofluorescence applications. It recognizes the mouse CD4 antigen with high specificity and sensitivity, allowing for precise identification and characterization of CD4-expressing cells in various biological samples.CD4, a coreceptor expressed on the surface of T helper cells, plays a pivotal role in immune system function by orchestrating immune responses and regulating the activation of other immune cells.

Understanding the expression and behavior of CD4-positive cells is essential for studying immune-mediated diseases, infection, and immune responses to various stimuli. The Mouse CD4 Monoclonal Antibody (AF488 Conjugated, GK1.5) AGEL1253 provides researchers with a reliable tool to investigate CD4 biology in-depth, offering valuable insights into immune system dynamics and potential therapeutic targets for immunomodulation strategies.

Product Title:GenieFluor 488 Anti-Mouse CD4 Antibody [GK1.5]
SKU:AGEL1253
Size:25µg, 100µg
Clone No:GK1.5
Synonyms:T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;L3T4;T4;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P06332
Gene ID:12504
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.

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