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PE Anti-Mouse CD38 Antibody [NIMR5] (AGEL2011)

SKU:
AGEL2011
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€99 - €219
Frequently bought together:

Description

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PE Anti-Mouse CD38 Antibody [NIMR5]

The Mouse CD38 Monoclonal Antibody (PE Conjugated) (NIMR5) is a specialized antibody designed for research involving CD38, a cell surface protein with roles in immune regulation and cell signaling. This monoclonal antibody, generated using advanced technology, is highly specific and reactive with mouse samples, making it ideal for flow cytometry and immunofluorescence applications. It binds specifically to the CD38 protein, enabling precise detection and analysis in various cell types, particularly in studies related to immunology and hematological disorders.

CD38 plays a crucial role in immune cell activation, proliferation, and differentiation, making it a key target for research in immunology, cancer biology, and autoimmune diseases. Understanding the function and expression of CD38 is essential for unraveling its impact on immune responses and disease pathogenesis. This monoclonal antibody provides researchers with a valuable tool for investigating the mechanisms underlying CD38-mediated immune regulation and exploring potential therapeutic strategies for manipulating CD38 pathways in disease contexts.

Product Title:PE Anti-Mouse CD38 Antibody [NIMR5]
SKU:AGEL2011
Size:50 Tests, 100 Tests, 200 Tests
Clone No:NIMR5
Synonyms:ADP-ribosyl cyclase 1;ADPRC 1;CD38;NIM-R5 antigen;2'-phospho-cyclic-ADP-ribose transferase;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P56528
Gene ID:12494
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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