The Mouse CD326 Monoclonal Antibody PE Conjugated (G8.8) is a cutting-edge research tool designed for investigations involving CD326, a cell surface marker associated with epithelial cells and cancer stem cells. This monoclonal antibody, conjugated with phycoerythrin (PE), allows for precise detection and analysis of CD326 expression in mouse samples. The G8.8 antibody specifically targets the CD326 protein, enabling researchers to explore its role in various cellular processes, particularly in the fields of stem cell biology and cancer research.CD326, also known as EpCAM (Epithelial Cell Adhesion Molecule), is a crucial player in cell adhesion, proliferation, and differentiation, making it a key marker in identifying and isolating stem cells and cancer-initiating cells.
Its significance in tissue regeneration and tumorigenesis underscores the importance of studying CD326 expression patterns and functions in different biological contexts. By utilizing the Mouse CD326 Monoclonal Antibody PE Conjugated (G8.8), researchers can gain valuable insights into the role of CD326 in epithelial cell biology, cancer development, and therapeutic targeting strategies.
Product Title:
PE Anti-Mouse CD326 Antibody [G8.8]
SKU:
AGEL1931
Size:
25µg, 100µg
Clone No:
G8.8
Synonyms:
Tacstd1;EpCAM;Ep-CAM;Megp314;EGP314;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q99JW5
Gene ID:
17075
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
EpCAM (CD326) mediates calcium-independent homophilic cell to cell adhesion. It may also function as a growth factor receptor. It is thought to be involved in maintaining cells in position during proliferation. Expression of EpCAM seems to correlate inversely with the level of E-cadherin (CD324). EpCAM is considered important in tumor biology.