The Mouse CD326 Monoclonal Antibody (FITC Conjugated, G8.8) is a valuable tool for researchers studying CD326, a cell surface marker associated with epithelial cell adhesion and tumor progression. This antibody, generated from mouse cells, demonstrates high specificity and sensitivity in detecting CD326 in mouse samples, making it suitable for flow cytometry and immunofluorescence applications. By binding to CD326, the antibody enables precise identification and analysis of epithelial cells, facilitating investigations in cancer biology, stem cell research, and developmental biology.CD326, also known as EpCAM (Epithelial Cell Adhesion Molecule), is a key protein involved in cell-cell adhesion and signaling pathways regulating cell proliferation and differentiation.
Its overexpression has been linked to various types of cancers, including carcinomas of the breast, colon, and lung. Understanding the role of CD326 in tumor development and progression is crucial for developing targeted therapies and diagnostic tools for these malignancies. This antibody provides researchers with a reliable tool to explore the functions and mechanisms of CD326 in diverse biological contexts, advancing our understanding of epithelial cell biology and cancer pathogenesis.
Product Title:
FITC Anti-Mouse CD326 Antibody [G8.8]
SKU:
AGEL1927
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
G8.8
Synonyms:
Tacstd1;EpCAM;Ep-CAM;Megp314;EGP314;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q99JW5
Gene ID:
17075
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
EpCAM (CD326) mediates calcium-independent homophilic cell to cell adhesion. It may also function as a growth factor receptor. It is thought to be involved in maintaining cells in position during proliferation. Expression of EpCAM seems to correlate inversely with the level of E-cadherin (CD324). EpCAM is considered important in tumor biology.