The Mouse CD31 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, AGEL1924) offered by Assaygenie is a highly specific and reliable tool for research in the field of immunology. This monoclonal antibody is designed to target CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), a key marker of endothelial cells and leukocytes.With its PerCP-Cyanine5.5 conjugation, this antibody allows for convenient flow cytometry applications, enabling researchers to accurately identify and analyze CD31 expression in various cell populations. The high specificity and sensitivity of this antibody make it an essential tool for studying vascular biology, angiogenesis, inflammation, and immune cell interactions.
CD31 plays a crucial role in mediating cell adhesion, migration, and signaling processes involved in immune responses and vascular function. By using the Mouse CD31 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, AGEL1924), researchers can gain valuable insights into the functions of CD31 in physiological and pathological conditions, including cancer, cardiovascular diseases, and inflammatory disorders.Advance your research with the precision and quality offered by the Mouse CD31 Monoclonal Antibody from Assaygenie.
Product Title:
PerCP/Cyanine5.5 Anti-Mouse CD31 Antibody [390]
SKU:
AGEL1924
Size:
25µg, 100µg
Clone No:
390
Synonyms:
Pecam; Pecam-1;PECAM-1;CD31;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q08481
Gene ID:
18613
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.