The Mouse CD31 Monoclonal Antibody PERCP-Cyanine5.5 Conjugated (AGeL1915) is an essential tool for researchers studying vascular biology and immunology. This monoclonal antibody specifically targets CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), a cell surface glycoprotein involved in various cellular processes, including leukocyte migration and angiogenesis.With its PERCP-Cyanine5.5 conjugation, this antibody offers excellent fluorescence intensity and stability for flow cytometry applications, enabling precise and reliable detection of CD31 expression on various cell types. Whether investigating endothelial cell function, angiogenesis, or immune cell interactions, this antibody provides valuable insights into the role of CD31 in these processes.
The Mouse CD31 Monoclonal Antibody PERCP-Cyanine5.5 Conjugated (AGeL1915) is meticulously validated for use in flow cytometry, allowing for reliable and reproducible results in experimental settings. Its high specificity and sensitivity make it an indispensable tool for researchers exploring the intricate mechanisms of vascular biology and immune system regulation.Unlock the potential of your research with the Mouse CD31 Monoclonal Antibody PERCP-Cyanine5.5 Conjugated (AGeL1915) and delve deeper into the fascinating world of CD31-mediated cellular interactions and signaling pathways.
Product Title:
PerCP/Cyanine5.5 Anti-Mouse CD31 Antibody [390]
SKU:
AGEL1915
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
390
Synonyms:
Pecam; Pecam-1;PECAM-1;CD31;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q08481
Gene ID:
18613
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.