The Mouse CD31 Monoclonal Antibody (PE/Cyanine5 Conjugated) is a specialized antibody designed for research applications involving CD31, a well-known marker of endothelial cells and platelets. This antibody, conjugated with PE/Cyanine5, facilitates the detection and analysis of CD31 expression with high specificity and sensitivity.CD31, also known as Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1), is a transmembrane glycoprotein involved in various cellular functions, including adhesion, migration, and signaling in the immune response and vascular biology. As a crucial player in mediating interactions between cells and the endothelium, CD31 is essential for maintaining vascular integrity and regulating inflammatory processes.The Mouse CD31 Monoclonal Antibody (PE/Cyanine5 Conjugated) is suitable for flow cytometry and immunofluorescence applications, enabling researchers to explore the expression and localization of CD31 in different tissues and cell types.
With its exceptional performance and reliability, this antibody is a valuable tool for studies focusing on angiogenesis, inflammation, cardiovascular diseases, and immune cell trafficking.By using this antibody, researchers can gain insights into the role of CD31 in various physiological and pathological conditions, advancing our understanding of vascular biology and immune system regulation. Its versatility and specificity make it an indispensable reagent for investigations aiming to unravel the complexities of CD31-mediated processes and their implications in health and disease.Ensure accurate and reliable results in your experiments with the Mouse CD31 Monoclonal Antibody (PE/Cyanine5 Conjugated) from Assay Genie – a trusted partner in high-quality research reagents.
Product Title:
PE/Cyanine5 Anti-Mouse CD31 Antibody [390]
SKU:
AGEL1921
Size:
25µg, 100µg
Clone No:
390
Synonyms:
Pecam; Pecam-1;PECAM-1;CD31;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q08481
Gene ID:
18613
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.