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PE/Cyanine5.5 Anti-Mouse CD31 Antibody [390] (AGEL1923)

SKU:
AGEL1923
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€199 - €499
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD31 Antibody [390]

The Mouse CD31 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) is a specialized tool for researchers studying vascular biology and endothelial cells. CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), is a transmembrane glycoprotein expressed on the surface of endothelial cells, platelets, and leukocytes. This antibody, conjugated with PE/Cyanine5.5, allows for easy detection and visualization of CD31 in flow cytometry applications, providing valuable insights into angiogenesis, inflammation, and vascular permeability.With its high specificity and sensitivity, this monoclonal antibody enables precise identification and analysis of CD31 expression in mouse samples.

By targeting this key endothelial marker, researchers can delve deeper into the mechanisms underlying vascular development, angiogenic processes, and immune cell interactions within the vasculature. Whether investigating cardiovascular diseases, tumor angiogenesis, or inflammatory responses, the Mouse CD31 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) is a trustworthy asset for advancing vascular research and understanding endothelial cell functions in diverse biological contexts.

Product Title:PE/Cyanine5.5 Anti-Mouse CD31 Antibody [390]
SKU:AGEL1923
Size:25µg, 100µg
Clone No:390
Synonyms:Pecam; Pecam-1;PECAM-1;CD31;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q08481
Gene ID:18613
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

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