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PE Anti-Mouse CD31 Antibody [390] (AGEL1910)

SKU:
AGEL1910
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
390
Conjugation:
PE
$251 - $599
Frequently bought together:

Description

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PE Anti-Mouse CD31 Antibody [390]

The Mouse CD31 Monoclonal Antibody (PE Conjugated) is a powerful tool designed for the detection and analysis of CD31, a cell surface glycoprotein known for its role in regulating various biological processes such as angiogenesis, inflammation, and immune response. This antibody, derived from mouse origin, exhibits high specificity and sensitivity in binding to the CD31 antigen, allowing for precise visualization and quantification of CD31 expression in different tissues and cell types.CD31, also referred to as platelet endothelial cell adhesion molecule (PECAM-1), plays a crucial role in mediating cell adhesion and signal transduction, thereby influencing vascular integrity and immune cell migration. Its involvement in diverse physiological and pathological processes, including tumor progression and cardiovascular diseases, has made CD31 a key molecule of interest in research fields like oncology, immunology, and vascular biology.

By enabling the specific targeting and analysis of CD31, this monoclonal antibody facilitates detailed investigations into the intricate mechanisms underlying CD31-mediated functions and associated pathological conditions.With its PE conjugation, this antibody offers enhanced signal detection capabilities, making it particularly suitable for flow cytometry and immunofluorescence applications. Researchers can rely on the Mouse CD31 Monoclonal Antibody (PE Conjugated) to unlock valuable insights into the complex biology of CD31 and its implications in health and disease, paving the way for advancements in therapeutic strategies targeting CD31-related pathways.

Product Title:PE Anti-Mouse CD31 Antibody [390]
SKU:AGEL1910
Size:50 Tests, 100 Tests, 200 Tests
Clone No:390
Synonyms:Pecam; Pecam-1;PECAM-1;CD31;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08481
Gene ID:18613
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

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