The Mouse CD31 Monoclonal Antibody (FITC Conjugated) is a vital tool for researchers investigating CD31, a key cell surface marker involved in vascular biology and endothelial cell function. This monoclonal antibody, derived from mouse hybridoma cells, exhibits high specificity and sensitivity when detecting CD31 in mouse samples, making it a valuable asset for various research applications.CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), plays a crucial role in various physiological processes, including leukocyte trafficking, angiogenesis, and vascular integrity. Its expression on endothelial cells and immune cells makes it a valuable target for studying vascular diseases, inflammatory disorders, and cancer progression.
By using this FITC-conjugated monoclonal antibody, researchers can accurately detect and quantify CD31 expression in different tissue types, facilitating in-depth analysis and understanding of its function in health and disease.Overall, the Mouse CD31 Monoclonal Antibody (FITC Conjugated) is an essential resource for researchers seeking to unravel the intricate roles of CD31 in vascular biology and immunology, paving the way for advancements in therapeutic strategies targeting CD31-related pathways.
Product Title:
FITC Anti-Mouse CD31 Antibody [390]
SKU:
AGEL1909
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
390
Synonyms:
Pecam; Pecam-1;PECAM-1;CD31;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q08481
Gene ID:
18613
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.