The Mouse CD31 Monoclonal Antibody (AF647 Conjugated) (AGEL1926) from AssayGenie is a high-quality antibody specifically designed for targeted research applications involving CD31, a key cell surface marker associated with endothelial cells and angiogenesis. This monoclonal antibody, conjugated with AF647 for fluorescent detection, offers exceptional sensitivity and specificity in various experimental techniques.CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a vital molecule involved in various physiological processes, including angiogenesis, immune response, and vascular homeostasis. By targeting CD31, researchers can gain valuable insights into endothelial cell function, vascular biology, and angiogenic processes in both normal and pathological conditions.
With its fluorescent conjugation, this mouse monoclonal antibody provides researchers with a powerful tool for visualizing CD31 expression in tissues, cell cultures, and various experimental models. Its high specificity ensures accurate detection and analysis of CD31-positive cells, making it ideal for studies in vascular biology, immunology, and cancer research.By utilizing the Mouse CD31 Monoclonal Antibody (AF647 Conjugated) (AGEL1926) from AssayGenie, researchers can advance their understanding of CD31 biology and its implications in health and disease, paving the way for discoveries in fields such as cardiovascular research, tumor angiogenesis, and therapeutic development.
Product Title:
GenieFluor 647 Anti-Mouse CD31 Antibody [390]
SKU:
AGEL1926
Size:
25µg, 100µg
Clone No:
390
Synonyms:
Pecam; Pecam-1;PECAM-1;CD31;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q08481
Gene ID:
18613
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.