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GenieFluor 647 Anti-Mouse CD31 Antibody [390] (AGEL1917)

SKU:
AGEL1917
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$347 - $851
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD31 Antibody [390]

The Mouse CD31 Monoclonal Antibody (AF647 Conjugated) is a specialized tool for researchers studying CD31, a key marker of endothelial cells and platelets. This antibody, created through monoclonal technology, is highly specific to mouse samples and is optimized for use in fluorescence microscopy and flow cytometry applications. By targeting the CD31 protein, this antibody allows for precise visualization and analysis of endothelial cells and platelets in various tissues, providing valuable insight into vascular biology, angiogenesis, and thrombosis.

CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), plays a crucial role in maintaining vascular integrity and regulating immune cell trafficking. Its expression on endothelial cells and platelets makes it a valuable biomarker for studying processes such as inflammation, angiogenesis, and coagulation. Research into CD31 can lead to a better understanding of cardiovascular diseases, cancer metastasis, and immune-mediated disorders, ultimately contributing to the development of targeted therapies and diagnostic tools.

Product Title:GenieFluor 647 Anti-Mouse CD31 Antibody [390]
SKU:AGEL1917
Size:50 Tests, 100 Tests, 200 Tests
Clone No:390
Synonyms:Pecam; Pecam-1;PECAM-1;CD31;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08481
Gene ID:18613
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

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