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GenieFluor 488 Anti-Mouse CD31 Antibody [390] (AGEL1925)

SKU:
AGEL1925
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€209 - €429

Description

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GenieFluor 488 Anti-Mouse CD31 Antibody [390]

The Mouse CD31 Monoclonal Antibody (AF488 conjugated) is a powerful tool for researchers studying vascular biology and endothelial cells. This antibody, designated as 390 (AGEL1925), specifically targets CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), which is a cell surface glycoprotein involved in endothelial cell adhesion and signaling.Developed for use in immunofluorescence applications, this antibody is conjugated with AF488, a fluorescent dye that emits a bright green signal when excited by appropriate wavelengths of light. This feature allows for visualization and localization of CD31 within cells and tissues with high specificity and sensitivity. Researchers can effectively examine CD31 expression patterns, cell morphology, and interactions in various experimental settings.

The unique binding specificity of this monoclonal antibody enables precise detection and quantification of CD31 expression in mouse samples, facilitating detailed analysis of endothelial cells and their functions. By targeting CD31, researchers can gain insights into vascular development, angiogenesis, inflammation, and other processes where endothelial cells play a critical role.Overall, the Mouse CD31 Monoclonal Antibody (AF488 conjugated) 390 (AGEL1925) serves as an indispensable tool for investigating endothelial biology and understanding the role of CD31 in physiological and pathological conditions, offering valuable data for studies in vascular biology, angiogenesis, and related fields.

Product Title:GenieFluor 488 Anti-Mouse CD31 Antibody [390]
SKU:AGEL1925
Size:25µg, 100µg
Clone No:390
Synonyms:Pecam; Pecam-1;PECAM-1;CD31;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q08481
Gene ID:18613
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

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