The Mouse CD31 Monoclonal Antibody (AF488 Conjugated- 390-AGEL1916) from AssayGenie is a cutting-edge research tool designed for scientists investigating CD31, a key cell surface marker involved in vascular biology and inflammation. This monoclonal antibody, conjugated with AF488 for enhanced detection capabilities, is developed specifically for use in flow cytometry and immunofluorescence applications.CD31, also known as platelet endothelial cell adhesion molecule, plays a critical role in endothelial cell biology, leukocyte migration, and angiogenesis. It is a widely recognized marker for endothelial cells and is crucial in studying vascular development, inflammation, and cardiovascular diseases. The AF488-conjugated CD31 antibody enables precise visualization and quantification of CD31 expression in various tissues and cell types, making it a valuable tool for researchers exploring angiogenesis, vascular biology, and immune responses.
With its high specificity and sensitivity, the Mouse CD31 Monoclonal Antibody (AF488 Conjugated- 390-AGEL1916) offers researchers the opportunity to delve deeper into the intricate mechanisms underlying vascular function and inflammation. By targeting CD31, scientists can uncover novel insights into disease pathogenesis, therapeutic developments, and potential diagnostic markers in a wide range of research fields including cardiovascular biology, immunology, and cancer research.
Product Title:
GenieFluor 488 Anti-Mouse CD31 Antibody [390]
SKU:
AGEL1916
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
390
Synonyms:
Pecam; Pecam-1;PECAM-1;CD31;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q08481
Gene ID:
18613
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.