The Mouse CD3 Monoclonal Antibody PERCP Conjugated (17A2) is a vital tool for immunological research involving the CD3 protein, a key component of the T-cell receptor complex. This antibody, derived from mouse hybridoma cells, is specifically conjugated with PERCP for flow cytometry applications, allowing for precise detection and analysis of T-cells in various samples.CD3 is essential for T-cell activation and function, playing a crucial role in adaptive immunity. By targeting the CD3 protein, researchers can explore T-cell responses in conditions such as infections, autoimmune diseases, and cancer. The monoclonal antibody 17A2 offers high specificity and sensitivity, making it an ideal choice for studies aiming to characterize T-cell populations and understand their roles in immune processes.
With its ability to recognize and bind to CD3 on T-cells, this antibody facilitates the identification and profiling of T-cell subsets, offering valuable insights into immune responses and contributing to advancements in immunotherapy and vaccine development. Researchers across immunology, oncology, and infectious diseases can benefit from the precision and reliability of the Mouse CD3 Monoclonal Antibody PERCP Conjugated (17A2) in their experimental investigations.
Product Title:
PerCP Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL0101
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PerCP Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.