The Mouse CD3 Monoclonal Antibody PE-Cy5 Conjugated (17A2-AGEL0102) is a powerful tool for immunology researchers investigating T cell function and activation. This antibody specifically targets the CD3 antigen, a crucial component of the T cell receptor complex that plays a central role in T cell signaling and activation.By binding to the CD3 antigen, this monoclonal antibody allows for the detection and analysis of T cells in various experimental settings. The PE-Cy5 conjugation provides excellent fluorescent signal intensity, making it ideal for flow cytometry applications and multiplexing experiments.The high specificity and sensitivity of this antibody, derived from mouse origin, ensure reliable and reproducible results in studies focused on T cell biology, immune response modulation, and autoimmune diseases.
Its versatility and consistent performance make it a valuable tool for researchers seeking to deepen their understanding of T cell function and immune regulation mechanisms.With its potential applications in immunology, cancer research, and infectious diseases, the Mouse CD3 Monoclonal Antibody PE-Cy5 Conjugated (17A2-AGEL0102) is a valuable asset for scientists looking to advance their research in the field of T cell biology and immune system modulation.
Product Title:
PE/Cyanine5 Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL0102
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.