The Mouse CD3 Monoclonal Antibody (PE-Conjugated, 17A2, AGEL0656) offered by AssayGenie is a powerful tool for immunological research involving the CD3 antigen present on T cells. This high-quality antibody, conjugated with phycoerythrin (PE), allows for easy and specific detection of CD3 in flow cytometry and immunofluorescence applications.The CD3 antigen is essential for T cell receptor signaling and plays a crucial role in T cell activation and function. By targeting CD3, researchers can accurately identify and study T cells in various biological samples, gaining insights into immune responses, infectious diseases, autoimmune disorders, and cancer immunology.
With its specificity and sensitivity, the Mouse CD3 Monoclonal Antibody (PE-Conjugated, 17A2, AGEL0656) is a reliable reagent for investigating T cell biology and immunotherapy. Trust AssayGenie for your immunological research needs and unlock the potential of CD3 analysis in your studies.
Product Title:
PE Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL0656
Size:
25µg, 100µg
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.