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GenieFluor 488 Anti-Mouse CD3 Antibody [17A2] (AGEL0103)

SKU:
AGEL0103
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
17A2
Conjugation:
AF 488
Applications:
FC
€119 - €269

Description

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GenieFluor 488 Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (Alexa Fluor 488 Conjugated, 17A2, AGEL0103) is a powerful tool for immunology research, specifically designed for detecting the CD3 protein in mouse samples. CD3 is a crucial component of the T-cell receptor complex, essential for T-cell activation and function in the immune response.This monoclonal antibody, labeled with Alexa Fluor 488 for fluorescence-based assays, offers high specificity and sensitivity in detecting CD3 expression in various cell types and tissues. Its conjugation with Alexa Fluor 488 facilitates fluorescent imaging and flow cytometry applications, enabling researchers to explore T-cell biology and immune responses in detail.With its validated performance in immunofluorescence and flow cytometry, the Mouse CD3 Monoclonal Antibody is ideal for studies focusing on T-cell activation, differentiation, and function.

By targeting the CD3 protein, this antibody provides valuable insights into the mechanisms underlying immune responses, autoimmune diseases, and infectious conditions in mouse models.Researchers in immunology, cancer biology, and infectious disease research can leverage the specificity and reliability of the Mouse CD3 Monoclonal Antibody (Alexa Fluor 488 Conjugated, 17A2, AGEL0103) to advance their understanding of T-cell biology and contribute to the development of innovative therapeutic strategies.

Product Title:GenieFluor 488 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0103
Size:50 Tests, 100 Tests, 200 Tests
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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